THE TUDOR DOMAIN PROTEIN SPINDLIN1 IS INVOLVED IN INTRINSIC ANTIVIRAL DEFENSE AGAINST INCOMING HEPATITIS B VIRUS AND HERPES SIMPLEX VIRUS TYPE 1.

The Tudor domain protein Spindlin1 is involved in intrinsic antiviral defense against incoming hepatitis B Virus and herpes simplex virus type 1.

Hepatitis B virus infection (HBV) is a major risk factor for the development of hepatocellular carcinoma.HBV replicates from a covalently closed circular DNA (cccDNA) that remains as an episome within the nucleus of infected cells and serves as a template for the transcription of HBV RNAs.The regulatory protein here HBx has been shown to be essenti

read more